A research carried out at Maranhao University in Brazil in 2014 evaluated the effect of treatment with a propolis hydroalcoholic extract produced by stingless bees in a murine asthma model. The data showed that propolis reduced the pathology associated with murine asthma by inhibiting the inflammatory cells migration to the alveolar space and the systemic progression of the allergic inflammation. Farias, J.H.C.D., Reis, A.S., Araújo, M.A.R., Araújo, M.J.A.M., Assunção, A.K.M., Farias, J.C.D., Fialho, E.M.S., Silva, L.A., Costa, G.C., Guerra, R.N.M. and Ribeiro, M.N.S., 2014. Effects of stingless bee propolis on experimental asthma. Evidence-Based Complementary and Alternative Medicine, 2014.

Based on a study conducted at Cairo University in 2003 asthma patients were treated with propolis for two months. The results demonstrated positive effects such as a reduction in the frequency and strength of night asthma attacks and improvement in respiratory functions. Khayyal, M.T., El-Ghazaly, M.A., El-Khatib, A.S., Hatem, A.M., Vried, P.J.F., El-Shafei, S. and Khattab, M.M. 2003. A clinical pharmacological study of the potential beneficial effects of a propolis food product as an adjuvant in asthmatic patients. Fundamental and Clinical Pharmacology 17: 93-102.

A scientific study carried out at Nanjing Medical University in 2016 investigated the effect of caffeic acid phenethyl ester (CAPE) of propolis on patients suffering from asthma. The findings of the study demonstrated that CAPE in propolis regulated airway microenvironment by relieving the inflammation. Hence, scientists proposed that the CAPE can be a potent agent for asthma management (3). Ma, Y., Zhang, J.X., Liu, Y.N. Ge, A., Gu, H., Zha, W.J., Zheng, X.N., and Huang, M. 2016. Caffeic acid phenethyl ester alleviates asthma by regulating the airway microenvironment via the ROS-responsive MAPK/Akt pathway. Free Radical Biology and Medicine 101: 163-175.

1. Farias, J.H.C., Reis, A.S., Araujo, M.A.R., Araujo, M.R.A.M., Assuncao, A.K.M. Farias, J.C., Fialho, E.M.S., Silva, L.A., Costa, G.C., Guerra, R.N.M., Ribeiro, M.N.S. and Nascimento, F.R.F. 2014. Effects of Stingless Bee Propolis on Experimental Asthma. Evidence Based Complementary and Alternative Medicine. 5: 951478.
2. Khayyal, M.T., El-Ghazaly, M.A., El-Khatib, A.S., Hatem, A.M., Vried, P.J.F., El-Shafei, S. and Khattab, M.M. 2003. A clinical pharmacological study of the potential beneficial effects of a propolis food product as an adjuvant in asthmatic patients. Fundamental and Clinical Pharmacology 17: 93-102.
3. Ma, Y., Zhang, J.X., Liu, Y.N. Ge, A., Gu, H., Zha, W.J., Zheng, X.N. and Huang, M. 2016. Caffeic acid phenethyl ester alleviates asthma by regulating the airway microenvironment via the ROS-responsive MAPK/Akt pathway. Free Radical Biology and Medicine 101: 163-175