Collagen constitutes about one-third of whole-body proteins, and it is the main structural protein of various connective tissues such as skin and cartilage in the body. Collagen has many vital functions, including building skin, bones, tendons, and ligaments, making cartilage, which is the flexible tissue between bones and in ears and nose, and creating muscles and blood vessels. Several factors influence the appearance, structure, and integrity of the skin, such as aging, hormones, UV radiation, and nutrition.
A study carried out at Hodeidah University in 2012 evaluated the causal microbial agents of Upper Respiratory Tract (URT) infections in children and the susceptibility of isolates to antibiotics and propolis as a naturally antimicrobial substance. The efficacy of propolis as a treatment of URT infections in 41 pediatric patients was tested.
Propolis, is a natural product collected from the stems, leaves and buds of the plants by the bees. Raw honey is a ready to eat food after it is harvested from the hives. There is no need to heat or to filter raw honey as such treatments removes or destroys the pollens. These all-natural bee products have antioxidant, antiviral, antibacterial, and anti-inflammatory activities.
Nothing is more worthy than the health of our kids. That's why we care very much about their diet with all-natural foods. One of the most well-known natural, nutritious food is royal jelly! It contains B-complex vitamins and minerals of magnesium, calcium, and iron in addition to 10-HDA and royalactin. Research carried out at Children's Hospital of Assiut University in 2016 investigated the immunomodulatory effects of fresh royal jelly administration on systemic lupus erythematosus (SLE) in children.
Bee bread is a natural product produced from the pollen of which the outer coat is digested by the intrinsic enzymes on the bees, rendering its nutrients become bioavailable. As the outer coat of pollen is fermented, many beneficial bacteria such as Lactic acid bacteria grow, and it becomes more digestible. Hence, bee bread is a healthy probiotic food due to the presence of Lactobacillus bacteria.
Joint research of the Pharmaceutical Sciences Faculty of Kyushu University and Food Science Department of Campinas University in 2008 investigated the antiviral efficacy of propolis extracts against influenza viruses (flu) under in vivo and in vitro conditions. The experimental design involved oral feeding of virus-infected mice with propolis extracts at different doses of 0.4 mg/kg, 2 mg/kg ve 10 mg/kg three times during seven days, while the control group received none. The scientists reported a faster recovery in the symptoms in mice treated with propolis depending on the increase in dosage. The observed positive effects on body weight and the survival times of infected mice were related to the antiviral activity of propolis, blocking the growth of the virus...
Recent reports demonstrate that the COVID-19 virus binds to the ACE-2 enzyme on the cell membrane, facilitating its entry. Then the virus leaves its RNA for multiplication, resulting in the development of pneumonia and many symptoms such as shorth breathing. So, a critical question is what compounds or drugs prevent the entrance of the virus into our cells. Many scientific studies propose that symptoms of viral infection can be reduced and controlled by blocking the ACE-2 enzyme binding sites. Is propolis capable of inhibiting the ACE-2 enzyme? "A scientific study conducted at Florida University in 2008 reported that ACE, the angiotensin-converting enzyme, is responsible for making ACE2 enzyme from ACE1 protein. In other words, it means that if there no ACE enzyme in the environment, there would be no ACE2 enzyme present in the cells. That means viruses cannot enter into the cells and multiply.
A study carried out at Sao Paulo University, Brasil, in 2013, investigated the influence of propolis on the growth of Candida Albicans fungus, which causes a variety of skin and soft tissue infections in healthy people. The experiment evaluated the growth of three strains of Candida Albicans at 30oC for 16 h under in vitro conditions.
Research carried out at the Pharmaceutical School of Campinas University in 2008 investigated the effectiveness of propolis on the influenza virus, causing common flu under in vitro conditions in mice. The experiment was conducted with propolis prepared in alcohol. The results of the study showed that propolis was effective in controlling the reproduction of the virus and decreased flu symptoms. The scientists suggested that alcohol extract of propolis is a beneficial dietary supplement for humans against the influenza virus.
Research conducted at Otto Von Guericke University, Germany, in 2003 demonstrated that propolis and its flavonoid constituents suppressed cytokines causing inflammation in human body cells and improved the immunomodulatory regulation. The study investigated the effects of different propolis extracts, of the flavonoids hesperidin, quercetin, and caffeic acid phenethyl ester (CAPE) on human immune cell functions. The results showed that propolis and its constituents suppressed phytohemagglutinin-induced DNA synthesis of peripheral blood mononuclear cells and T cells in addition to different types of cytokines. In contrast, the production of TGF-beta1 by T regulatory cells was increased. Those results indicated a direct regulatory effect of propolis on the basic functional properties of immune cells. The scientists propose that propolis can be a powerful natural anti-inflammatory medicine influencing different types of immune responses.